Sorry if this is not an appropriate place to post. Move me if you like. I have tried the Wacom forum but it doesn't seem that busy.
I have two monitors on a WinXP system and an A3 Graphics tablet. The tablet splits half-half down the middle but this makes the thing go out of proportion to the screen. It's OK for mouse-work, point and click but hopeless for tricky selecting and drawing. For instance, drawing a perfect circle on the tablet makes an elipse on screen.
I have been in the Wacom set-up utility but much of it is beyond my technical ability. I think it has something to do with mapping but that's as much as I can work out.