If you will not be scanning slides and film I would go with the Epson 3490 just based on price. If you plan to scan negatives and slides the Epson 4490 is better.
Vue Scan and Silverfast are advanced drivers. Silverfast is too pricey IMO and might not be even available for that level of scanner. Vue Scan is more reasonable and can give better quality scans than the manufacturer's driver. I have Vue Scan and find I do just as well in an image editor after the scan if I am careful with the histogram to not clip any information.