I feel that "standard" seems to be "safer" based on the sharpening aspect that "Eric S" mentioned (hope I understood that part)
You get more compression artifacts with standard than with fine. Compression artifacts are bad. You enhance those artifacts with sharpening.
Use standard for your vacation, but don't consider standard "safer" once you get back home and can download the pictures to your computer. Fine is safer.
Most of Steve's outdoor sample shots are 4Mp + in fine, which isn't bad compression. I would guess real-world standard shots will come out in the 2Mb range. Not great but probably acceptable.