Welcome to the PC. It's probably not that different from the Mac world once you familiarize yourself a little with Windows. I'd recommend downloading the Qimage demo and working with that to familiarize yourself, but yes, Qimage is compatible with the 4000 as we have many Epson 4000 owners who also own Qimage. The installation process should be simple. Just install the latest Epson 4000 Windows driver and then install Qimage. You'll be able to select the 4000 in Qimage as your printer, and just start with the "Getting familiar..." section of the help in Qimage. You can post here or email me if you have any questions.